47 approved radiopharmaceuticals for FDA
views：time：2017-09-13 14:28:44
1、Drug name：Fluorine-18sodium fluoride（18F-sodium fluoride）
Manufacturer：Various
Trade name：—
Use: bone forming agent for bone formation
2、Drug name：Fluorine-18florbetapir（18F-AV45）
Manufacturer：Eli Lilly
Trade name：Amyvid
Purpose: diagnosis and treatment of Alzheimer's disease
3、Drug name：Fluorine-18 florbetaben（18F-AV1）
Manufacturer：Piramal Imaging
Trade name：Neuraceq
Uses: Blzheimer (AD) patients and patients with dementia
4、Drug name：Fluorine-18fludeoxyglucose（18F-FDG）
Manufacturer：Various
Trade name：—
Purpose: to detect the abnormal metabolism of glucose in tumor and epileptic focus
5、Drug name：Fluorine-18flutemetamol（18F-PIB）
Manufacturer：GE Healthcare
Trade name：Vizamyl
Uses: Blzheimer (AD) patients and patients with dementia
6、Drug name：Iodine I-123iobenguane（123I-MIBG）
Manufacturer：GE Healthcare
Trade name：AdreView
Purpose: auxiliary diagnosis of primary or metastatic pheochromocytoma or neuroblastoma
7、Drug name：Carbon-11 choline（11C-choline）
Manufacturer：Mayo Clinic
Trade name：—
Purpose: prostate cancer recurrence diagnosis
8、Drug name：Gallium-67 citrate（67Ga-citric acid）
Manufacturer：Lantheus MedicalImaging、Mallinckrodt
Trade name：—
Uses: Hodgkin's disease, lymphoma, bronchogenic carcinoma, and some acute inflammatory diseases
9、Drug name：Indium-111capromab pendetide（111In-Carol mAb）
Manufacturer：AytuPharmaceuticals
Trade name：ProstaScint?
Uses: prostate cancer patients, prostate cancer patients suspected of metastasis after the detection
10、Drug name：Indium-111 chloride（111In-Indium chloride）
Manufacturer：GE Healthcare、Mallinckrodt
Trade name：Indiclor
Usage: used in radioactive labeling
11、Drug name：Indium-111 pentetate（111In-DTPA）
Manufacturer：GE Healthcare
Trade name：—
Purpose: radionuclide cerebral angiography
12、Drug name：Indium-111oxyquinoline（111In-8-hydroxyquinoline）
Manufacturer：GE Healthcare
Trade name：—
Uses: used for autologous leukocyte markers, diagnosis of inflammation and infection
13、Drug name：Indium-111pentetreotide（111In-octreotide）
Manufacturer：Mallinckrodt
Trade name：Octreoscan
Purpose: primary and metastatic neuroendocrine tumors, localization of somatostatin receptors
14、Drug name：Iodine I-123iobenguane（123I-MIBG）
Manufacturer：GE Healthcare
Trade name：AdreView
Purpose: auxiliary diagnosis of primary or metastatic pheochromocytoma or neuroblastoma
15、Drug name：Carbon-14 urea（14C-urea）
Manufacturer：Kimberly-Clark
Trade name：PYtest
Purpose: diagnosis of Helicobacter pylori infection in the stomach
16、Drug name：Iodine I-123sodium iodide capsules（123I-Sodium Iodide Capsules）
Manufacturer：Cardinal Health、Mallinckrodt
Trade name：—
Uses: evaluation of thyroid function and morphology
17、Drug name：Iodine I-125 humanserum albumin（125I-human serum albumin）
Manufacturer：IsoTex Diagnostics
Trade name：Jeanatope
Usage: Determination of whole blood and plasma volume
18、Drug name：Iodine I-125iothalamate（125I-Phthalate）
Manufacturer：IsoTex Diagnostics
Trade name：Glofil-125
Purpose: evaluation of glomerular filtration rate
19、Drug name：Iodine I-131 humanserum albumin（131I-human serum albumin）
Manufacturer：IsoTex Diagnostics
Trade name：Megatope
Uses: blood and plasma volume, cardiac output, cardiac and pulmonary blood volume, protein turnover, brain tumor location, etc.
20、Drug name：Iodine I-131sodium iodide（131I-Sodium iodide）
Manufacturer：DRAXIMAGE、Mallinckrodt
Trade name：HICON
Purpose: diagnosis and treatment of thyroid diseases
21、Drug name：MolybdenumMo-99 generator（Molybdenum technetium generator）
Manufacturer：GE Healthcare、Lantheus MedicalImaging、Mallinckrodt
Trade name：DRYTEC、Technelite、UltraTechneKow?DTE
Uses: preparation of radiopharmaceuticals
22、Drug name：Nitrogen-13 ammonia（13N-ammonia）
Manufacturer：Various
Trade name：—
Purpose: myocardial perfusion evaluation of coronary artery disease
23、Drug name：Radium-223 dichloride（223Ra-Two radium chloride）
Manufacturer：Bayer HealthCarePharmaceuticalsInc.
Trade name：Xofigo
Uses: castration resistant prostate cancer
24、Drug name：Rubidium-82 chloride（82Ru-Rubidium chloride）
Manufacturer：Bracco Diagnostics
Trade name：Cardiogen-82
Purpose: myocardial perfusion imaging agent
25、Drug name：Samarium-153lexidronam（153Sm-EDTMP）
Manufacturer：Lantheus MedicalImaging
Trade name：Quadramet?
Uses: reduces pain in patients with bone metastases
26、Drug name：Strontium-89 chloride（89Sr-Strontium chloride）
Manufacturer：GE Healthcare
Trade name：MetastronTM
Uses: reduces pain in patients with bone metastases
27、Drug name：Technetium-99mbicisate（99mTc-ECD）
Manufacturer：Lantheus MedicalImaging
Trade name：Neurolite
Purpose: diagnosis and treatment of stroke in stroke patients
28、Drug name：Technetium-99mdisofenin（99mTc-Strychnine）
Manufacturer：Pharmalucence
Trade name：Hepatolite
Purpose: acute cholecystitis diagnosis
29、Drug name：Technetium-99mexametazine（99mTc-HMPAO）
Manufacturer：GE Healthcare
Trade name：Ceretec
Purpose: blood brain perfusion and leukocyte marker imaging in patients with cerebral apoplexy are used for abdominal infection and intestinal inflammation localization
30、Drug name：Technetium-99mmacroaggregatedalbumin（99mTc-MAA）
Manufacturer：DRAXIMAGE
Trade name：—
Application: evaluation of pulmonary perfusion and evaluation of patency of abdominal venous shunt
31、Drug name：Technetium-99mmebrofenin（99mTc-Mebrofenin）
Manufacturer：Bracco Diagnostics、Pharmalucence
Trade name：Choletec
Usage: hepatobiliary imaging agent
32、Drug name：Technetium-99mmedronate（99mTc-MDP）
Manufacturer：DRAXIMAGE、GE Healthcare、Pharmalucence
Trade name：MDP-25、MDP Multidose
Purpose: bone imaging agent
33、Drug name：Technetium-99mmertiatide（99mTc-MAG3）
Manufacturer：Mallinckrodt
Trade name：TechnescanMAG3TM
Purpose: renal dynamic imaging
34、Drug name：Technetium-99moxidronate（99mTc-HDP）
Manufacturer：Mallinckrodt
Trade name：TechnescanHDP
Purpose: bone imaging agent
35、Drug name：Technetium-99mpentetate（99mTc-DTPA）
Manufacturer：DRAXIMAGE
Trade name：—
Purpose: brain imaging and renal imaging
36、Drug name：Technetium-99mpyrophosphate（99mTc-PYP）
Manufacturer：Mallinckrodt、Pharmalucence
Trade name：Technescan、PYP
Uses: bone imaging, cardiac imaging agents, and blood pool imaging agents
37、Drug name：Technetium-99m redblood cells（99mTc-Red blood cell）
Manufacturer：Mallinckrodt
Trade name：UltraTag?
Uses: blood pool radiography, digestive tract bleeding localization
38、Drug name：Technetium-99msestamibi（99mTc-MIBI）
Manufacturer：Cardinal Health、DRAXIMAGE、Lantheus MedicalImaging、Mallinckrodt、Pharmalucence
Trade name：Cardiolite
Purpose: myocardial perfusion is used to detect ischemia, evaluate neurological function, and breast imaging
39、Drug name：Technetium-99msodium pertechnetate（99mTc-Technetium sodium salt）
Manufacturer：GE Healthcare、Lantheus MedicalImaging、Mallinckrodt
Trade name：—
Uses: brain imaging, thyroid imaging, placental localization, bladder imaging, etc.
40、Drug name：Technetium-99msuccimer（99mTc-DMSA）
Manufacturer：GE Healthcare
Trade name：—
Purpose: renal imaging
41、Drug name：Technetium-99msulfur colloid（99mTc-Sulfur colloid）
Manufacturer：Pharmalucence
Trade name：—
Uses: liver, spleen, bone marrow imaging and so on
42、Drug name：Technetium-99mtetrofosmin（99mTc-Substituted phosphine）
Manufacturer：GE Healthcare
Trade name：MyoviewTM
Uses: myocardial perfusion agent
43、Drug name：Technetium-99mtilmanocept（99mTc-The horse for Nuosai）
Manufacturer：NavideaBiopharmaceuticals,Inc.
Trade name：Lymphoseek
Purpose: lymph node localization
44、Drug name：Thallium-201chloride（201Tl-Thallium chloride）
Manufacturer：GE Healthcare、Lantheus MedicalImaging、Mallinckrodt
Trade name：—
Purpose: myocardial perfusion imaging
45、Drug name：Xenon-133 gas（133XeGas）
Manufacturer：Lantheus MedicalImaging
Trade name：—
Purpose: pulmonary function evaluation, lung imaging, and cerebral blood flow evaluation
46、Drug name：Yttrium-90chloride（90Y-Yttrium chloride）
Manufacturer：MDS Nordion、Eckert＆ZieglerNuclitec
Trade name：—
Usage: radioactive mark
47、Drug name：Yttrium-90ibritumomab tiuxetan（90Y-Ibritumomab tiuxetan）
Manufacturer：SpectrumPharmaceuticals
Trade name：Zevalin
Purpose: non Hodge's lymphoma treatment
